<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2025 Workiva-->
<!--r:52f1bdcb-4bd3-48d3-899f-d4b34486d47a,g:d0000ae0-25b1-482f-995c-d6d1a5d401a6-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.lantheus.com/role/Cover" xlink:type="simple" xlink:href="lnth-20250226.xsd#Cover"/>
  <link:presentationLink xlink:role="http://www.lantheus.com/role/Cover" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_9a1427b8-ef8a-4163-b3d5-0d0aefecb84c" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_DocumentType_9a1427b8-ef8a-4163-b3d5-0d0aefecb84c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_47ed630a-01a8-40f6-8b8d-725a1de22822" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_DocumentPeriodEndDate_47ed630a-01a8-40f6-8b8d-725a1de22822" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_d3edf8b3-de01-419f-8f3d-8236b7dae39d" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_EntityRegistrantName_d3edf8b3-de01-419f-8f3d-8236b7dae39d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_fbeb400a-e158-45fc-9402-6e284fe3a4ff" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_EntityIncorporationStateCountryCode_fbeb400a-e158-45fc-9402-6e284fe3a4ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_93683ced-f817-4624-a82b-2fb63ec9a74c" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_EntityFileNumber_93683ced-f817-4624-a82b-2fb63ec9a74c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_e8fbf41d-8ea7-4eec-af3b-9746bffecb53" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_EntityTaxIdentificationNumber_e8fbf41d-8ea7-4eec-af3b-9746bffecb53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_199a4068-e91d-43a7-ad16-f0f517b32e47" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_EntityAddressAddressLine1_199a4068-e91d-43a7-ad16-f0f517b32e47" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_0d0def99-d849-4490-836a-480300fbb086" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_EntityAddressCityOrTown_0d0def99-d849-4490-836a-480300fbb086" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_054f54be-3790-494b-ba51-b41fd0f61d11" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_EntityAddressStateOrProvince_054f54be-3790-494b-ba51-b41fd0f61d11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_a09080a5-531a-4ea3-954c-ab9e5d75077d" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_EntityAddressPostalZipCode_a09080a5-531a-4ea3-954c-ab9e5d75077d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_10396654-2ab5-4fe7-844f-b4acc590127e" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_CityAreaCode_10396654-2ab5-4fe7-844f-b4acc590127e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_a2e9fe9e-26bc-4dfe-a533-6bc6f6099c4f" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_LocalPhoneNumber_a2e9fe9e-26bc-4dfe-a533-6bc6f6099c4f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_4a71504f-4044-45dd-9133-f4883fb10b46" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_WrittenCommunications_4a71504f-4044-45dd-9133-f4883fb10b46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_51ffe198-3dc8-41aa-b02a-c751ef98f25c" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_SolicitingMaterial_51ffe198-3dc8-41aa-b02a-c751ef98f25c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_37a9c7fa-fe55-496d-9ac2-a66e09e2a10b" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_PreCommencementTenderOffer_37a9c7fa-fe55-496d-9ac2-a66e09e2a10b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_39737188-3e50-422c-8020-88149ab612c5" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_39737188-3e50-422c-8020-88149ab612c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_75a2926f-0816-44ea-a568-6635fc744d98" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_Security12bTitle_75a2926f-0816-44ea-a568-6635fc744d98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_c08270c2-e670-4ed1-b7f0-3b3b889f61a5" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_TradingSymbol_c08270c2-e670-4ed1-b7f0-3b3b889f61a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_63bb5a4d-5443-49e6-bed9-5e5a4252698e" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_SecurityExchangeName_63bb5a4d-5443-49e6-bed9-5e5a4252698e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_6ddd3861-21dc-4e87-b936-5ff3284d5135" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_EntityEmergingGrowthCompany_6ddd3861-21dc-4e87-b936-5ff3284d5135" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_22a18384-bfd1-4872-86eb-98d945a7301f" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_AmendmentFlag_22a18384-bfd1-4872-86eb-98d945a7301f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_256bee69-1091-4df8-8f9a-a643b8e0f3e4" xlink:href="https://xbrl.sec.gov/dei/2024/dei-2024.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_523b8fc0-b038-4c6f-a012-ca29767dd927" xlink:to="loc_dei_EntityCentralIndexKey_256bee69-1091-4df8-8f9a-a643b8e0f3e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
